From the README:
By including almond in the built file, there is no need for RequireJS. almond is 948 bytes when minified with Closure Compiler and gzipped.
Since it can support certain types of loader plugin-optimized resources, it is a great fit for a library that wants to use text templates or CoffeeScript as part of their project, but get a tiny download in one file after using the RequireJS Optimizer.
If you are building a library, the wrap=true support in the RequireJS optimizer will wrap the optimized file in a closure, so the define/require AMD API does not escape the file. Users of your optimized file will only see the global API you decide to export, not the AMD API. See the usage section below for more details.
So, you get great code cleanliness with AMD and the use of powerful loader plugins in a tiny wrapper that makes it easy for others to use your code even if they do not use AMD.